A database of hormones and their receptors |
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HMRbase accession number | 20359 |
Swiss-prot Accession number | Q16950 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 1 receptor (5-HTB1) (Serotonin receptor 1). |
Source organism | Aplysia californica (California sea hare) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Reproductive system. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin). 5-HT plays important roles in various behavioral and physiological processes in aplysia. These include feeding, locomotion, circadian rhythm, learning and memory, synaptic plasticity, and synaptic growth. This receptor is mediated by G proteins that stimulate phospholipase C. |
Protein Length | 453 Amino acids |
Molecular weight | 50622 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7472509 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20360 |
Swiss-prot Accession number | Q16951 (Sequence in FASTA format) |
Description | 5-hydroxytryptamine 2 receptor (5-HTB2) (Serotonin receptor 2). |
Source organism | Aplysia californica (California sea hare) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia. |
Subcellular location | Cell membrane; multi-pass membrane protein |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | Central nervous system. |
Post translational modification | N/A |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin). 5-HT plays important roles in various behavioral and physiological processes in aplysia. These include feeding, locomotion, circadian rhythm, learning and memory, synaptic plasticity, and synaptic growth. This receptor is mediated by G proteins that stimulate phospholipase C. |
Protein Length | 421 Amino acids |
Molecular weight | 47637 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 7472509 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20369 |
Swiss-prot Accession number | O76267 (Sequence in FASTA format) |
Description | G-protein-coupled 5-hydroxytryptamine receptor. |
Source organism | Aplysia californica (California sea hare) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 492 Amino acids |
Molecular weight | 56262 |
Domain Name | 7tm_1 |
References | 1 PubMed abstract 9671650 |
Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 20414 |
Swiss-prot Accession number | Q8MX83 (Sequence in FASTA format) |
Description | G-protein-coupled 5-hydroxytryptamine receptor 2. |
Source organism | Aplysia californica (California sea hare) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia. |
Subcellular location | Membrane (By similarity) |
Developmental Stage | N/A |
Similarity | Belongs to the G-protein coupled receptor 1 family. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 567 Amino acids |
Molecular weight | 63167 |
Domain Name | 7tm_1 |
References | 1 Barbas D., Zappulla J.P., Angers S., Bouvier M., Castellucci V.F.,DesGroseillers L.; "Molecular characterization of a new serotoninergic receptornegatively coupled to adenylate cyclase in Aplysia californica."; Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
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Hormone | N/A |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments | !Hormone for this Receptor are either unknown or have not yet been curated |
HMRbase accession number | 22210 |
Swiss-prot Accession number | Q6VU64 (Sequence in FASTA format) |
Description | Estrogen receptor |
Source organism | Aplysia californica (California sea hare) |
Taxonomical Classification | Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda;Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea;Aplysioidea; Aplysiidae; Aplysia. |
Subcellular location | N/A |
Developmental Stage | N/A |
Similarity | Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain. |
Tissue Specificity | N/A |
Post translational modification | N/A |
Function | N/A |
Protein Length | 477 Amino acids |
Molecular weight | 52661 |
Domain Name | Hormone_recep zf-C4 |
References | 1 PubMed abstract 14500980 |
Hormone | Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase Detail in HMRbase |
Gene ID | N/A |
PDB ID | N/A |
Drugpedia | wiki |
Comments |